Pilot-Scale & Commercial-Scale Manufacture
Porton’s core manufacturing competencies span the range from where a process requires sufficient characterization and moderate quantities of material to enable clinical proof-of-concept [typically Phase II], all the way to achieving very substantial cost efficiencies in support of large-volume production as a product faces loss of exclusivity challenges [late life cycle management]. Our production sites are strategically and technologically differentiated [dedicated respectively to APIs / advanced intermediates, regulatory starting materials and true starting materials] to deliver high-quality manufacturing solutions and powerfully back-integrated cost-of-goods advantages to our customers. Please see below for a snapshot of Porton’s production sites:
Highly Flexible Mulit-Purpose Site
Total Reactor Capacity: 706 cubic meters
2 Pilot Plants
10 Commercial Scale Workshops
Wide Range of Chemistry Capabilities including High Pressure Hydrogenations, Asymmetric Synthesis and Hazardous Reactions
Glass-Lined Steel, SS and Hastelloy Reactors Last Successful US FDA Inspection in September 2015 >75 Big Pharma cGMP and EHS Audits Successfully Received Since 2012.
Shangyu [Shanghai Area]
Highly Flexible, Multi-Purpose Site for Regulated Starting Materials for Supply Directly to Global Customers, or to Porton Changshou for Conversion to Advanced Intermediates or APIs.
Total Reactor Capacity 180 cubic meters. Green Field Option for Capacity Expansion Available.
Pilot Plant and Commercial Scale Workshop
Wide Range of Chemical Competencies.
GMP Upgrade to Type II Materials in Process for Completion end-2016
Key Site for Cost-Advantageous Back-Integration of Starting Materials
Total Reactor Capacity 470 cubic meters
Extensive Experience of Supplying Quality Starting Materials to Porton Changshou and Shangyu Sites
Wide Range of Chemical Competencies, Especially Hazardous Chemistry